Analysis into conolidine has brought about discovery of the opioid receptor in the body called ACKR3/CXCR7. ACKR3 is apparently probably the most desired focus on for conolidine, which also disregards the other 4 classical opioid receptors(3). thank you.. A: There is restricted info on contraindications in between Conolidine and https://www.proleviate.com/post/conolidine-an-alternative-natural-pain-relief-to-replace-traditional-painkillers