Atrial septal defect (ASD) is a congenital heart defect characterized by an opening in the atrial septum. About 1/3 of patients with Noonan syndrome caused by mutation in the PTPN11 gene have ASD. The prevalence of ASD is estimated at 100 per 100. 000 live births. https://www.diegojavierfares.com/mega-save-8-tall-Faux-Crystal-Beaded-Candle-Holder-Centerpiece-great-buy/