Not all sufferers with CLL require therapy. Inspite of all recent improvements, the iwCLL even now suggests watchful observation for patients with asymptomatic sickness.86 This advice relies on at least two randomized trials comparing observation to either chlorambucil monotherapy or fludarabine, cyclophosphamide and rituximab (FCR).103,104 Both trials concluded that early https://edgarmctix.bloggosite.com/39232738/examine-this-report-on-mbl77