Not all individuals with CLL have to have therapy. Inspite of all recent developments, the iwCLL however suggests watchful observation for people with asymptomatic disease.86 This recommendation is based on at the least two randomized trials comparing observation to either chlorambucil monotherapy or fludarabine, cyclophosphamide and rituximab (FCR).103,104 Each trials https://emmau887ese1.snack-blog.com/profile