Hofmann’s Focus on ergot led him down a route of isolating and synthesizing its compounds. The focus was on making a respiratory and circulatory stimulant. Convulsive ergotism is characterized by anxious dysfunction, in which the target is twisting and contorting their human body in ache, trembling and shaking, and wryneck, https://medium.com/@LsdWorld/the-future-of-lsd-research-and-potential-medical-uses-40ebd16dd150