Sign transduction; receptor; animal types; preclinical; pharmacodynamics; pharmacokinetics; drug development; drug metabolism The universality of DNA methylation as an epigenetic regulatory mechanism belongs to all Organic kingdoms. Even so, when eukaryotic methods are already the primary emphasis of DNA methylation experiments, the molecular mechanisms in prokaryotes are much less re... https://www.directivepublications.org/the-journal-of-molecular-biology/